From: Subject: Healthbeat: Stress and Chronic Pain : News : WHOI Online Date: Tue, 6 Jun 2006 16:30:11 -0400 MIME-Version: 1.0 Content-Type: multipart/related; type="text/html"; boundary="----=_NextPart_000_0020_01C68986.7B496B70" X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2900.2869 This is a multi-part message in MIME format. ------=_NextPart_000_0020_01C68986.7B496B70 Content-Type: text/html; charset="utf-8" Content-Transfer-Encoding: quoted-printable Content-Location: http://www.hoinews.com/news/news_story.aspx?id=3234 =EF=BB=BF Healthbeat: Stress = and Chronic Pain : News : WHOI Online
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Healthbeat: Stress and Chronic Pain


By Jen=20 Christensen
Posted: Thursday, = March 09, 2006=20 at 7:46 PM

Fibromyalgia =
Fibromyalgia=20 is a condition that is characterized by serious, widespread = chronic joint=20 and muscle pain. The pain is often described as shooting, = throbbing,=20 aching, burning or twitching. The intensity of the pain varies and = may be=20 worse in the early morning, or after exposure to cold or humid = weather,=20 excessive activity and stress and anxiety.

The pain and = tenderness=20 associated with fibromyalgia is most severe at 18 specific areas = of the=20 body, called tender points. Those tender points are located in the = area of=20 the neck, elbows, hips and knees. Although there is no specific = test for=20 fibromyalgia, the condition is considered when other causes of the = pain=20 have been ruled out, pain persists for at least three months, and = patients=20 experience pain in at least 11 of the 18 tender=20 points.

Fibromyalgia also causes several other symptoms. = Patients=20 can experience severe, debilitating fatigue, numbness or tingling = in parts=20 of the body, sensitivity to odors, bright lights or loud noises, = sleep=20 problems, headaches, digestive problems, impairment in memory and=20 concentration, dry eyes, restless legs syndrome, dizziness, pelvic = pain=20 (in women), problems with coordination and = depression.

According to=20 the National Fibromyalgia Association, up to six percent of = Americans have=20 fibromyalgia. About 80 to 90 percent of patients are women. The = condition=20 can occur at any age, but is most commonly diagnosed between 20 = and 50.=20 The cause is unknown. However, patients with rheumatic diseases = (like=20 rheumatoid arthritis, lupus, and ankylosing spondylitis) appear to = be at=20 higher risk for the condition. Fibromyalgia also tends to run in = families,=20 but researchers are uncertain if genetics or environmental factors = play a=20 role in the increased risk.

The Role of Stress=20
Researchers at the University of Alabama at Birmingham = recently=20 conducted a study to determine the role of stress on pain = perception in=20 patients with fibromyalgia. Patients with the condition may = respond=20 differently to stress than healthy people.

Investigators = recruited=20 120 patients with fibromyalgia and 60 healthy control patients. In = the=20 first part of the study, participants were asked to image a = stressful or=20 neutral event from their past. Then a heat stimulus was applied to = the=20 skin of the arm for a few minutes. Researchers measured heart = rate, blood=20 pressure and cortisol levels (a stress hormone) in the blood. = Patients=20 also rated the intensity and unpleasantness of the pain.

In = the=20 second part of the study, researchers repeated the same testing = conditions=20 with the heat stimulus. But this time, images of the brain were = taken. The=20 images allow investigators to study the differences in blood flow = to the=20 brain during periods of stressful and nonstressful = pain.

Laurence=20 Bradley, Ph.D., a Chronic Pain Researcher at the University of = Alabama at=20 Birmingham, says pain has both a sensory component and an = emotional=20 component. Sometimes our emotional response to pain has a great = influence=20 in how we perceive the pain. Preliminary results from the study = show=20 patients with fibromyalgia tend to rate the heat stimulus as much = more=20 unpleasant than healthy control subjects. Bradley says, if the = results=20 show that emotions play an important role in pain perception for = those=20 with fibromyalgia, doctors may want to consider treating = depression in=20 patients with higher levels of the emotional symptoms. That may = help some=20 fibromyalgia patients gain better control over their pain=20 symptoms.

The researchers are now performing a second study = to find=20 out if brothers and sisters of patients with fibromyalgia also = have a=20 greater sensitivity to pain than brothers and sisters of healthy = control=20 subjects. The information may help doctors determine if genetic = factors=20 may be related to the development of fibromyalgia.

AUDIENCE INQUIRY
For information on=20 fibromyalgia:
American College of Rheumatology, http://www.rheumatology.org/
Arthritis = Foundation,=20 http://www.arthritis.org/
National = Fibromyalgia=20 Association, http://www.fmaware.org/
National Institute = of=20 Arthritis and Musculoskeletal and Skin Diseases, http://www.niams.nih.gov/
About Us | Contact = Us | Advertise = With Us |=20 Privacy=20 Policy | Spot = Runner | Terms of = Use
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